Search results for "general [bl lacertae objects]"
showing 10 items of 27644 documents
Virtudes escolares percibidas por estudiantes y docentes ecuatorianos: diferencias según sexo, establecimiento y roles
2020
El objetivo del estudio es evaluar la virtuosidad percibida en organizaciones escolares y las diferencias por tipo de centro educativo (fiscal, municipal); sexo (mujer, hombre) y rol (estudiantes, docentes). Se trató de un estudio instrumental basado en el análisis de la estructura factorial y la fiabilidad de un cuestionario para evaluar virtudes percibidas en escuelas (VPOE); y, de un estudio descriptivo transversal que analizó diferencias por sexo, rol y tipo de organizaciones escolares con relación a las virtudes percibidas. Se trabajó con una muestra de 550 estudiantes (49.28 % mujeres) y 105 docentes (47.62% mujeres). El análisis factorial determinó un modelo de cuatro factores que pe…
Conformational Dynamics of the Dengue Virus Protease Revealed by Fluorescence Correlation and Single-Molecule FRET Studies.
2021
The dengue virus protease (DENV-PR) represents an attractive target for counteracting DENV infections. It is generally assumed that DENV-PR can exist in an open and a closed conformation and that active site directed ligands stabilize the closed state. While crystal structures of both the open and the closed conformation were successfully resolved, information about the prevalence of these conformations in solution remains elusive. Herein, we address the question of whether there is an equilibrium between different conformations in solution which can be influenced by addition of a competitive inhibitor. To this end, DENV-PR was statistically labeled by two dye molecules constituting a FRET …
SARS-CoV-2 envelope protein topology in eukaryotic membranes
2020
Coronavirus E protein is a small membrane protein found in the virus envelope. Different coronavirus E proteins share striking biochemical and functional similarities, but sequence conservation is limited. In this report, we studied the E protein topology from the new SARS-CoV-2 virus both in microsomal membranes and in mammalian cells. Experimental data reveal that E protein is a single-spanning membrane protein with the N-terminus being translocated across the membrane, while the C-terminus is exposed to the cytoplasmic side (Nt lum /Ct cyt ). The defined membrane protein topology of SARS-CoV-2 E protein may provide a useful framework to understand its interaction with other viral and ho…
(A,B) In vivo GCaMP6f signals recorded in layers M1, M5 and M9/10 of Mi1 (A) and Tm3 (B) neurons, before (blue, green) and after (gray, red) applicat…
2019
Sensory systems sequentially extract increasingly complex features. ON and OFF pathways, for example, encode increases or decreases of a stimulus from a common input. This ON/OFF pathway split is thought to occur at individual synaptic connections through a sign-inverting synapse in one of the pathways. Here, we show that ON selectivity is a multisynaptic process in the Drosophila visual system. A pharmacogenetics approach demonstrates that both glutamatergic inhibition through GluClα and GABAergic inhibition through Rdl mediate ON responses. Although neurons postsynaptic to the glutamatergic ON pathway input L1 lose all responses in GluClα mutants, they are resistant to a cell-type-specifi…
Toimijuus korkeakoulutettujen suomen oppijoiden visuaalisissa narratiiveissa
2018
This socioculturally informed study explores how highly educated Finnish language learners represent their agency in visual narratives. Learners (n=59) were asked to draw two pictures of themselves as Finnish language users and provide verbal interpretations of the drawings. The aim of using visual narratives is to reach aspects such as feelings and beliefs which might be difficult to express verbally. The data were analyzed first by using visual grammar set out by Kress and van Leeuwen (2006) and secondly by content analysis. The findings suggest that learners saw Finnish language as a tool for oral communication. However, difficulties with speaking and listening appeared to restrict learn…
Impacts of Touch Screen Size, User Interface Design, and Subtask Boundaries on In-Car Task's Visual Demand and Driver Distraction
2020
Visual distraction by secondary in-car tasks is a major contributing factor in traffic incidents. In-car user interface design may mitigate these negative effects but to accomplish this, design factors’ visual distraction potential should be better understood. The effects of touch screen size, user interface design, and subtask boundaries on in-car task's visual demand and visual distraction potential were studied in two driving simulator experiments with 48 participants. Multilevel modeling was utilized to control the visual demands of driving and individual differences on in-car glance durations. The 2.5” larger touch screen slightly decreased the in-car glance durations and had a diminis…
Researching Children’s Multiple Family Relations: Social Network Maps and Life-Lines as Methods
2015
Visual methods are reported to have certain advantages when conducting interviews on sensitive topics, such as intimate spaces, home-related ethical issues, and vulnerable families. In this article, we concentrate on two visual methods: social network maps and life-lines. In our research project on children’s well-being and emotional security in multiple family relations, we collected data by interviewing children and asking them to complete social network maps and life-lines. We discuss the suitability of these two visual methods for describing children’s close relationships with their family members and significant others. Combining these two methods during an interview process with child…
Gas Emissions From the Western Aleutians Volcanic Arc
2021
The Aleutian Arc is remote and highly active volcanically. Its 4,000 km extent from mainland Alaska to Russia’s Kamchatka peninsula hosts over 140 volcanic centers of which about 50 have erupted in historic times. We present data of volcanic gas samples and gas emission measurements obtained during an expedition to the western-most segment of the arc in September 2015 in order to extend the sparse knowledge on volatile emissions from this remote but volcanically active region. Some of the volcanoes investigated here have not been sampled for gases before this writing. Our data show that all volcanoes host high-temperature magmatic-hydrothermal systems and have gas discharges typical of volc…
A Low-Cost Smartphone Sensor-Based UV Camera for Volcanic SO2 Emission Measurements
2017
Recently, we reported on the development of low-cost ultraviolet (UV) cameras, based on the modification of sensors designed for the smartphone market. These units are built around modified Raspberry Pi cameras (PiCams; ≈USD 25), and usable system sensitivity was demonstrated in the UVA and UVB spectral regions, of relevance to a number of application areas. Here, we report on the first deployment of PiCam devices in one such field: UV remote sensing of sulphur dioxide emissions from volcanoes; such data provide important insights into magmatic processes and are applied in hazard assessments. In particular, we report on field trials on Mt. Etna, where the utility of these devices in quantif…
Sulfur Degassing From Steam-Heated Crater Lakes: El Chichón (Chiapas, Mexico) and Víti (Iceland)
2018
The composition of the gases released by El Chichón (Chiapas, Mexico) and Víti (Askja volcano, Iceland) volcanic lakes is examined by Multi-GAS for the first time. Our results demonstrate that H2S and SO2 are degassed by these pH 2–3 lakes. We find higher CO2/H2S and H2/H2S ratios in the lakes' emissions (31–5,685 and 0.6–35, respectively) than in the fumarolic gases feeding the lakes (13–33 and 0.08–0.5, respectively), evidencing that only a fraction (0.2–5.4% at El Chichón) of the H2S(g) contributed by the subaquatic fumaroles ultimately reaches the atmosphere. At El Chichón, we estimate a H2S output from the crater lake of 0.02–0.06 t/day. Curiously, SO2 is also detected at trace levels …